Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

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Oxidative Stress and Insulin Resistance

OBJECTIVE Although cumulative evidence suggests that increased oxidative stress may lead to insulin resistance in vivo or in vitro, community-based studies are scarce. This study examined the longitudinal relationships of oxidative stress biomarkers with the development of insulin resistance and whether these relationships were independent of obesity in nondiabetic young adults. RESEARCH DESI...

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Oxidative Stress and Insulin Resistance Oxidative stress and insulin resistance: The CARDIA study

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2018

ISSN: 0021-9258

DOI: 10.1074/jbc.ra117.001254